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Mendocine scientists and a vaccine against chlamydia

In addition to the vaccine, the team is also working to determine the relationship of this infection to cancer, something
Science
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| 19 March, 2020 |

Anahí Capmani, molecular biologist, told the advances in research that led her to obtain the Outstanding Young Mendocinos 2019 award, presented by the Mendocino Entrepreneur Council (CEM), in the category of “academic achievements“. The scientist and team of the Biochemistry and Immunity Laboratory of the UNQUIU Faculty of Medical Sciences studies the bacteria Chlamydiatrachomatis,whichis sexually transmitted and is the main cause of infertility in women. They are close to creating a vaccine and a rapidtestfor early detection . Thisresearch that began in 2016also seeks to advance the study of this infection as a risk factor for cancer, something little explored in the world.

Much more than a cause of infertility

Chlamydia trachomatis is known as the leading cause of female infertility and affects most sexually active young women . When untreated, the bacteria can infect cervical cells, spread to the ovaries, fallopian tubes, or uterus causing pelvic inflammatory disease and inability to achieve or maintain a pregnancy.

However, these are not the only consequences it causes. In the biochemistry laboratory, Capmani studies chlamydia as a risk factor for cancer, something little explored. “Infertility is just an edge, chlamydia causes a lot more than that. So far there are epidemiological studies that say, by example, that some strains of HPV (Human Papillomavirus) cause cancer, but for that they need other factors are activated, and it has been seen that there are coinfections with chlamydia that generate cancer cells, but it is not yet all studied together, only now the issue is booming,” explained the biologist.

The scientist stressed that progress in molecular studies, the vaccine and analyze how The bacterium is important so that a more effective mechanism of attack can be posed, since in the chronic phase the infection is very difficult to eliminate.

A vaccine and a quick test

Another part of the research in the biochemistry laboratory of the UNCuyo is focused on finding a preventive method, a quick way to detect infection and a A drug that supplements antibiotics that are already used to attack Chlamydia.

The way to detect if a person has this infection is through laboratorytests – Yeah . The gynecologist Olivia Roca explained that there is a specific study of sampling in the cervix that is done when infection is suspected. In the case of men, the doctor takes a sample of the cells in the urethra. It can also be detected by a urine analysis.

To make detection faster and simpler, Capmani said that the team of researchers is working on a test that can be done in any room without requiring too much equipment. “The exam is held to do as when a woman is going to get a PAP or a Colposcopy. The idea is that it is a quick test to implement early detection and do a quick check,” he said.

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